The night shift can be brutal. Doctors, nurses, truck drivers and other professionals can be subject to the most gruelling shifts. Working a night shift can take its toll on your social life, your sleep cycle and your health. The limited exposure to the rest of society, perhaps even missing out on family time, can make you feel isolated and depressed. Furthermore, night shifts can throw off your routine as much as your circadian clock. If you switch between shifts, then your sleep cycle is hindered as is your ability to balance tasks.